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Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L)

Electron Microscopy / Cell Biology / Confocal Microscopy / Apoptosis / Biological Sciences / Caspases / Cell line / Humans / Animals / Cytochrome C / Monoclonal Antibodies / Proteins / Fluorescent Antibody Technique / The cell / Monoclonal Antibody / Cytoplasm / Apoptotic Protease Activating Factor-1 / Caspases / Cell line / Humans / Animals / Cytochrome C / Monoclonal Antibodies / Proteins / Fluorescent Antibody Technique / The cell / Monoclonal Antibody / Cytoplasm / Apoptotic Protease Activating Factor-1

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Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes

Electron Microscopy / Membrane Proteins / Cell Biology / Transcription Factors / Biological Sciences / Humans / HeLa cells / The cell / Eukaryotic Cells / Membrane Protein / Monoglycerides / Lysosomes / DNA binding proteins / Endosomes / Protein Transport / Protein Sorting / Humans / HeLa cells / The cell / Eukaryotic Cells / Membrane Protein / Monoglycerides / Lysosomes / DNA binding proteins / Endosomes / Protein Transport / Protein Sorting

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A cation counterflux supports lysosomal acidification

Physiology / Macrophages / Biological Sciences / Humans / Permeability / Mice / Animals / Medical Physiology / Anions / The cell / Lysosomes / Cations / Hydrogen-Ion Concentration / General Physiology / Mice / Animals / Medical Physiology / Anions / The cell / Lysosomes / Cations / Hydrogen-Ion Concentration / General Physiology

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Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor

Calcium / Immunohistochemistry / Cell Biology / Macrophages / Transcription Factors / Apoptosis / Cell Division / Signal Transduction / Biological Sciences / Mice / Animals / Phenotype / Eye / The cell / Osteoblasts / Bone and Bones / Apoptosis / Cell Division / Signal Transduction / Biological Sciences / Mice / Animals / Phenotype / Eye / The cell / Osteoblasts / Bone and Bones

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In Vivo Release of Mitotic Silencing of Ribosomal Gene Transcription Does Not Give Rise to Precursor Ribosomal RNA Processing

Cell Cycle / Cell Biology / RNA polymerase / Gene Silencing / Biological Sciences / Mitosis / Humans / ribosomal RNA / Colchicine / HeLa cells / Isoenzymes / The cell / Ribosomal DNA / Okadaic acid / Mitosis / Humans / ribosomal RNA / Colchicine / HeLa cells / Isoenzymes / The cell / Ribosomal DNA / Okadaic acid

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DNM1, a dynamin-related gene, participates in endosomal trafficking in yeast

Reproduction / Kinetics / Pheromones / Cell Biology / Biological Sciences / Saccharomyces cerevisiae / Mutation / G protein-coupled receptors / Endocytosis / Polymerase Chain Reaction / Genetic Map / Peptides / Molecular cloning / Fluorescent Antibody Technique / The cell / Amino Acid Profile / Amino Acid Sequence / Base Sequence / Ligands / Endosomes / Full Length Movies / Saccharomyces cerevisiae / Mutation / G protein-coupled receptors / Endocytosis / Polymerase Chain Reaction / Genetic Map / Peptides / Molecular cloning / Fluorescent Antibody Technique / The cell / Amino Acid Profile / Amino Acid Sequence / Base Sequence / Ligands / Endosomes / Full Length Movies

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A cation counterflux supports lysosomal acidification

Physiology / Macrophages / Biological Sciences / Humans / Permeability / Mice / Animals / Medical Physiology / Anions / The cell / Lysosomes / Cations / Hydrogen-Ion Concentration / General Physiology / Chlorides / Mice / Animals / Medical Physiology / Anions / The cell / Lysosomes / Cations / Hydrogen-Ion Concentration / General Physiology / Chlorides

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Golgi membranes contain an electrogenic H+ pump in parallel to a chloride conductance

Energy / Cell Biology / Biological Sciences / Animals / Membrane transport / Endoplasmic Reticulum / Potassium / Density gradient / Ion / Rats / Rat / Guanosine Triphosphate / The cell / Membrane Potential / Golgi Apparatus / Hydrogen-Ion Concentration / Electric Conductivity / Plasma Membrane / Ions / Adenosine Triphosphate / Chlorides / Endoplasmic Reticulum / Potassium / Density gradient / Ion / Rats / Rat / Guanosine Triphosphate / The cell / Membrane Potential / Golgi Apparatus / Hydrogen-Ion Concentration / Electric Conductivity / Plasma Membrane / Ions / Adenosine Triphosphate / Chlorides

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Intracellular Localization of Proteasomal Degradation of a Viral Antigen

Protein Folding / Enzyme Inhibitors / Cell Biology / Protein synthesis / Influenza virus / Biological Sciences / Molecular chaperones / Humans / Mutation / Antigen Presentation / Solubility / Fluorescent Antibody Technique / Multienzyme complexes / The cell / Cysteine endopeptidases / Protein Conformation / Canavanine / Protein Biosynthesis / PROTEASOME INHIBITOR / Biological Sciences / Molecular chaperones / Humans / Mutation / Antigen Presentation / Solubility / Fluorescent Antibody Technique / Multienzyme complexes / The cell / Cysteine endopeptidases / Protein Conformation / Canavanine / Protein Biosynthesis / PROTEASOME INHIBITOR

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Intracellular Localization of Proteasomal Degradation of a Viral Antigen

Protein Folding / Enzyme Inhibitors / Cell Biology / Protein synthesis / Influenza virus / Biological Sciences / Molecular chaperones / Humans / Mutation / Antigen Presentation / Solubility / Fluorescent Antibody Technique / Multienzyme complexes / The cell / Cysteine endopeptidases / Protein Conformation / Canavanine / Protein Biosynthesis / PROTEASOME INHIBITOR / Biological Sciences / Molecular chaperones / Humans / Mutation / Antigen Presentation / Solubility / Fluorescent Antibody Technique / Multienzyme complexes / The cell / Cysteine endopeptidases / Protein Conformation / Canavanine / Protein Biosynthesis / PROTEASOME INHIBITOR

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Sequestration of Mammalian Rad51-Recombination Protein into Micronuclei

Cell Cycle / DNA replication / Cell Biology / DNA damage / DNA repair / Biological Sciences / Humans / Micronuclei / Mice / Animals / Cell Death / T cells / Cell nucleus / Rats / The cell / Homologous Recombination / Cell Cycle Arrest / Recombinant Protein / Mutagens / DNA binding proteins / DNA double strand breaks / Biological Sciences / Humans / Micronuclei / Mice / Animals / Cell Death / T cells / Cell nucleus / Rats / The cell / Homologous Recombination / Cell Cycle Arrest / Recombinant Protein / Mutagens / DNA binding proteins / DNA double strand breaks

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Sequestration of Mammalian Rad51-Recombination Protein into Micronuclei

Cell Cycle / DNA replication / Cell Biology / DNA damage / DNA repair / Biological Sciences / Humans / Micronuclei / Mice / Animals / Cell Death / T cells / Cell nucleus / Rats / The cell / Homologous Recombination / Cell Cycle Arrest / Recombinant Protein / Mutagens / DNA binding proteins / DNA double strand breaks / Biological Sciences / Humans / Micronuclei / Mice / Animals / Cell Death / T cells / Cell nucleus / Rats / The cell / Homologous Recombination / Cell Cycle Arrest / Recombinant Protein / Mutagens / DNA binding proteins / DNA double strand breaks

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Intracellular Localization of Proteasomal Degradation of a Viral Antigen

Protein Folding / Enzyme Inhibitors / Cell Biology / Protein synthesis / Influenza virus / Biological Sciences / Molecular chaperones / Humans / Mutation / Antigen Presentation / Solubility / Fluorescent Antibody Technique / Multienzyme complexes / The cell / Cysteine endopeptidases / Protein Conformation / Canavanine / Protein Biosynthesis / PROTEASOME INHIBITOR / Biological Sciences / Molecular chaperones / Humans / Mutation / Antigen Presentation / Solubility / Fluorescent Antibody Technique / Multienzyme complexes / The cell / Cysteine endopeptidases / Protein Conformation / Canavanine / Protein Biosynthesis / PROTEASOME INHIBITOR

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Intracellular Localization of Proteasomal Degradation of a Viral Antigen

Protein Folding / Enzyme Inhibitors / Cell Biology / Protein synthesis / Influenza virus / Biological Sciences / Molecular chaperones / Humans / Mutation / Antigen Presentation / Solubility / Fluorescent Antibody Technique / Multienzyme complexes / The cell / Cysteine endopeptidases / Protein Conformation / Canavanine / Protein Biosynthesis / PROTEASOME INHIBITOR / Biological Sciences / Molecular chaperones / Humans / Mutation / Antigen Presentation / Solubility / Fluorescent Antibody Technique / Multienzyme complexes / The cell / Cysteine endopeptidases / Protein Conformation / Canavanine / Protein Biosynthesis / PROTEASOME INHIBITOR

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